In a mixing bowl, combine the ground beef, garlic powder, onion powder, cayenne pepper, Worcestershire sauce, salt, and pepper.

Mix the ingredients gently until well combined.

Divide the mixture into even-sized patties, shaping them with your hands. Avoid overworking the meat.

Preheat your grill or stovetop to medium-high heat.

Cook the patties for about 4-5 minutes on each side, or until desired doneness is reached.

Let the burgers rest for a few minutes before serving.